2. GPCR/G Protein
  3. Guanylate Cyclase
  4. Uroguanylin (human) TFA

Uroguanylin (human) (TFA) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) (TFA) has anti-tumor actions in an animal model for human colon cancer.

For research use only. We do not sell to patients.

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Uroguanylin (human) TFA Chemical Structure

Uroguanylin (human) TFA Chemical Structure

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500 μg In-stock

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Other Forms of Uroguanylin (human) TFA:

Uroguanylin (human) TFA Related Antibodies

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Description

Uroguanylin (human) (TFA) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) (TFA) has anti-tumor actions in an animal model for human colon cancer[1].

Molecular Weight

1667.86 (free base)

Formula

C64H102N18O26S4.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)
Sequence Shortening

NDDCELCVNVACTGCL (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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Uroguanylin (human) TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Uroguanylin (human)Guanylate CyclaseGuanylyl Cyclase (GCC) receptoranti-tumorcolon cancerInhibitorinhibitorinhibit

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