1. GPCR/G Protein
  2. Guanylate Cyclase
  3. Uroguanylin (human) TFA

Uroguanylin (human) (TFA) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) (TFA) has anti-tumor actions in an animal model for human colon cancer.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Uroguanylin (human) TFA Chemical Structure

Uroguanylin (human) TFA Chemical Structure

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500 μg In-stock

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Description

Uroguanylin (human) (TFA) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) (TFA) has anti-tumor actions in an animal model for human colon cancer[1].

Molecular Weight

1667.86 (free base)

Formula

C64H102N18O26S4.xC2HF3O2

Appearance

Solid

Sequence

Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)

Sequence Shortening

NDDCELCVNVACTGCL (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Uroguanylin (human) TFA
Cat. No.:
HY-P3099A
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