2. GPCR/G Protein
  3. Guanylate Cyclase
  4. Uroguanylin (human)

Uroguanylin (human) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) has anti-tumor actions in an animal model for human colon cancer.

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Uroguanylin (human) Chemical Structure

Uroguanylin (human) Chemical Structure

CAS No. : 154525-25-4

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Uroguanylin (human) Related Antibodies

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Description

Uroguanylin (human) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) has anti-tumor actions in an animal model for human colon cancer[1][2].

Molecular Weight

1667.86

Formula

C64H102N18O26S4
CAS No.
Sequence

Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)
Sequence Shortening

NDDCELCVNVACTGCL (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Uroguanylin (human) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Uroguanylin (human)154525-25-4Guanylate CyclaseGuanylyl Cyclase (GCC) receptoranti-tumorcolon cancerInhibitorinhibitorinhibit

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