2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite Phosphodiesterase (PDE)
  4. Vardenafil (dihydrochloride) (Standard)

Vardenafil (dihydrochloride) (Standard) 

Cat. No.: HY-B0442CR Purity: ≥98%
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Vardenafil (dihydrochloride) (Standard) is the analytical standard of Vardenafil (dihydrochloride). This product is intended for research and analytical applications. Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil dihydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM respectively, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil dihydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil dihydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes-.

For research use only. We do not sell to patients.

Vardenafil (dihydrochloride) (Standard) Chemical Structure

Vardenafil (dihydrochloride) (Standard) Chemical Structure

CAS No. : 224789-15-5

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Description

Vardenafil (dihydrochloride) (Standard) is the analytical standard of Vardenafil (dihydrochloride). This product is intended for research and analytical applications. Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil dihydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM respectively, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil dihydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil dihydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes-.

Molecular Weight

561.52

Formula

C23H34Cl2N6O4S
CAS No.
SMILES

O=C1N=C(C2=CC(S(=O)(N3CCN(CC)CC3)=O)=CC=C2OCC)NN4C1=C(C)N=C4CCC.[H]Cl.[H]Cl
Structure Classification
Initial Source
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Vardenafil (dihydrochloride) (Standard) Related Classifications

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Keywords:

Vardenafil (dihydrochloride) (Standard)224789-15-5Endogenous MetabolitePhosphodiesterase (PDE)cGMPselectivesmoothmuscleNOstimulationerectiledysfunctionvardenafilimpotencePharmacokineticserectile dysfunctionhepatitiszucker diabetic fatty ratsdiabetesInhibitorinhibitorinhibit

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