2. Immunology/Inflammation
  3. Complement System
  4. Vesencumab

Vesencumab  (Synonyms: MNRP-1685A)

Cat. No.: HY-P99386 Purity: 95.00%
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Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer.

For research use only. We do not sell to patients.

CAS No. : 1205533-60-3

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1 mg USD 480 In-stock
5 mg USD 1250 In-stock
10 mg USD 2000 In-stock
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Based on 1 publication(s) in Google Scholar

Vesencumab Related Antibodies

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Description

Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Human
IC50 & Target

neuropilin-1[1]
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Vesencumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized Neuropilin-1 Protein, Human (His) can bind Vesencumab. The EC50 for this effect is 5.571 ng/mL.
  • Loaded Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His, HY-P75814) on AHC2 biosensor, can bind Vesencumab with an affinity constant of 1.372E-09 M as determined in BLI assay.
Purity & Documentation

Purity: 95.00%

SDS (251 KB)

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Vesencumab Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vesencumab1205533-60-3MNRP-1685AComplement SystemIG1anti-angiogenicanti-neoplastictumorovarian cancerInhibitorinhibitorinhibit

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