2. Immunology/Inflammation
  3. CD3
  4. Vibecotamab

Vibecotamab  (Synonyms: XmAb14045)

Cat. No.: HY-P99521 Purity: 99.34%
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Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies.

For research use only. We do not sell to patients.

CAS No. : 2138442-13-2

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1 mg USD 850 In-stock
5 mg USD 2400 In-stock
10 mg USD 3800 In-stock
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Based on 1 publication(s) in Google Scholar

Vibecotamab Related Antibodies

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Description

Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies[1].

Isotype

half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3
Species

Chimeric
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Vibecotamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3
Biological Activity
  • Immobilized Vibecotamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 0.48 ng/mL.
  • Immobilized Vibecotamab can bind Human IL-3R alpha/CD123 Protein (ECD, His Tag). The EC50 for this effect is 7.66 ng/mL.
Purity & Documentation
References
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Vibecotamab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vibecotamab2138442-13-2XmAb14045XmAb 14045XmAb-14045CD3Cluster of differentiation 3CD123bispecific antibodyantitumormyeloid leukaemiaInhibitorinhibitorinhibit

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