2. GPCR/G Protein Immunology/Inflammation Anti-infection
  3. CCR HIV
  4. Vicriviroc malate

Vicriviroc malate  (Synonyms: SCH 417690 malate; SCH-D malate; MK-7690)

Cat. No.: HY-B0155B
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Vicriviroc (SCH 417690) malate is an orally active CCR5 antagonist with the IC50 of 10 nM, and also inhibts MIP-1α and intracellular calcium release induced by the ligand RANTES (10 nM) with the IC50 values of 0.91 nM and 16 nM,,respectively. Vicriviroc malate can inhibits human immunodeficiency virus type 1 (HIV-1) infection, and can also used for study of cancer.

For research use only. We do not sell to patients.

Vicriviroc malate Chemical Structure

Vicriviroc malate Chemical Structure

CAS No. : 541503-81-5

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Vicriviroc malate Related Antibodies

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

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Description

Vicriviroc (SCH 417690) malate is an orally active CCR5 antagonist with the IC50 of 10 nM, and also inhibts MIP-1α and intracellular calcium release induced by the ligand RANTES (10 nM) with the IC50 values of 0.91 nM and 16 nM,,respectively. Vicriviroc malate can inhibits human immunodeficiency virus type 1 (HIV-1) infection, and can also used for study of cancer[1][2].

Molecular Weight

667.72

Formula

C32H44F3N5O7
CAS No.
SMILES

COC[C@@H](C1=CC=C(C=C1)C(F)(F)F)N2[C@H](CN(C3(CCN(CC3)C(C4=C(C)N=CN=C4C)=O)C)CC2)C.O=C(O)C(O)CC(O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Vicriviroc malate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vicriviroc541503-81-5SCH 417690SCH-D MK-7690SCH417690SCH-417690MK7690MK 7690MK-7690CCRHIVCC chemokine receptorHuman immunodeficiency virusBa/F3-CCR5 cellsColorectal CancerHIV-1Inhibitorinhibitorinhibit

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