2. Anti-infection
  3. HIV
  4. Vif-ElonginC interaction inhibitor 1

Vif-ElonginC interaction inhibitor 1 (compound VEC-5) is a potent Vif inhibitor. Vif-ElonginC interaction inhibitor 1 can restrict HIV-1 in Vif-nonpermissive cells. Vif-ElonginC interaction inhibitor 1 can protect A3G, APOBEC3C (A3C), and APOBEC3F (A3F) from Vif-mediated degradation and drastically inhibit Vif function through blocking the interaction between Vif and ElonginC. Vif-ElonginC interaction inhibitor 1 enhances A3G incorporation into HIV-1 virions to reduce viral infectivity.

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Vif-ElonginC interaction inhibitor 1 Chemical Structure

Vif-ElonginC interaction inhibitor 1 Chemical Structure

CAS No. : 374679-27-3

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Vif-ElonginC interaction inhibitor 1 Related Antibodies

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Description

Vif-ElonginC interaction inhibitor 1 (compound VEC-5) is a potent Vif inhibitor. Vif-ElonginC interaction inhibitor 1 can restrict HIV-1 in Vif-nonpermissive cells. Vif-ElonginC interaction inhibitor 1 can protect A3G, APOBEC3C (A3C), and APOBEC3F (A3F) from Vif-mediated degradation and drastically inhibit Vif function through blocking the interaction between Vif and ElonginC. Vif-ElonginC interaction inhibitor 1 enhances A3G incorporation into HIV-1 virions to reduce viral infectivity[1].

Molecular Weight

447.48

Formula

C29H21NO4
CAS No.
SMILES

O=C(OCC)C1=C2C=C(C=CN2C(C(C3=CC=C4C=CC=CC4=C3)=O)=C1)C(C5=CC=CC=C5)=O
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Vif-ElonginC interaction inhibitor 1 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vif-ElonginC interaction inhibitor 1374679-27-3HIVHuman immunodeficiency virusVifHIV-1A3GAPOBEC3CA3CAPOBEC3FA3FElonginCviral infectivityInhibitorinhibitorinhibit

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