2. PROTAC Vitamin D Related/Nuclear Receptor
  3. AUTOTACs Androgen Receptor
  4. VinclozolinM2-2204

VinclozolinM2-2204 is a androgen receptor (AR) AUTOTAC degrader, with an DC50 of 200 nM in LNCaP prostate cancer cells. VinclozolinM2-2204 induces the formation of AR+LC3+ autophagic membranes. VinclozolinM2-2204 can be used for the research of cancer.(Pink: AR inhibitor (HY-168296); Black: linker (HY-128833); Blue: CRBN Ligand (HY-168293))

For research use only. We do not sell to patients.

VinclozolinM2-2204 Chemical Structure

VinclozolinM2-2204 Chemical Structure

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VinclozolinM2-2204 Related Antibodies

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Description

VinclozolinM2-2204 is a androgen receptor (AR) AUTOTAC degrader, with an DC50 of 200 nM in LNCaP prostate cancer cells. VinclozolinM2-2204 induces the formation of AR+LC3+ autophagic membranes. VinclozolinM2-2204 can be used for the research of cancer[1].(Pink: AR inhibitor (HY-168296); Black: linker (HY-128833); Blue: CRBN Ligand (HY-168293))

Molecular Weight

824.79

Formula

C43H51Cl2N3O9
SMILES

O[C@H](CNCCOCCOCCNC(N(C1=CC(Cl)=CC(Cl)=C1)C(C(C)(O)C=C)=O)=O)COC2=CC(OCCC3=CC=CC=C3)=C(OCCC4=CC=CC=C4)C=C2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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VinclozolinM2-2204 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VinclozolinM2-2204AUTOTACsAndrogen ReceptorAUTOphagy-TArgeting ChimerasLNCaPprostate cancerautophagic membranesARInhibitorinhibitorinhibit

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