Viridicatumtoxin

Name: Viridicatumtoxin
Brand: MedChemExpress
SKU: HY-129208
Rating: 4.5 (1 reviews)

Cat. No.: HY-129208: FAQs
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Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

For research use only. We do not sell to patients.

Viridicatumtoxin Chemical Structure

CAS No. : 39277-41-3

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

In Vivo

Viridicatumtoxin (60-400 mg/kg; i.p., p.o., s.c; ICR mice, Sprague-Dawley rats and mature Wistar rats (4/5 weeks; 16-20 g/140-150 g)) has no signs of toxicity with p.o. administration. As the dosage increasing (i.p. and p.o.), hepatocytes starts to have pathological changes and deaths occurrs in both mice and rats. Mice and rats which given the viridicatumtoxin by s.c. has no signs of toxicity and none die, but coagulation necrosis is present at the injection site^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	ICR mice, Sprague-Dawley rats and mature Wistar rats (4/5 weeks; 16-20 g/140-150 g)^[2]
Dosage:	60-400 mg/kg
Administration:	i.p., p.o., s.c.
Result:	Orally with viridicatumtoxin had no signs of toxicity. As the dosage increasing (i.p. and p.o.), hepatocytes started to have pathological changes and deaths occurred in both mice and rats. Mice and rats which given the viridicatumtoxin by s.c. had no signs of toxicity and none died, but coagulation necrosis was present at the injection site.

Molecular Weight

565.57

Formula

C₃₀H₃₁NO₁₀

CAS No.

39277-41-3

SMILES

CC1(C(C2)(C(C)=CCC1)C3=C(OC)C=C(O)C4=C(O)C(C(C5(O)C(O)(CC(O)=C(C(N)=O)C5=O)C6O)=O)=C6C2=C34)C

Structure Classification

Initial Source

Microorganisms

Penicillium viridicatum Westling

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hutchison RD, et al. Viridicatumtoxin, a new mycotoxin from Penicillium viridicatum Westling. Toxicol Appl Pharmacol. 1973;24(3):507-509. [Content Brief]

[2]. Bendele AM, Carlton WW, Nelson GE, Peterson RE, Grove MD. Viridicatumtoxin mycotoxicosis in mice and rats. Toxicol Lett. 1984;22(3):287-291. [Content Brief]