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Virstatin inhibits the pili system synthesis and prevents A. baumannii biofilm formation. Virstatin also inhibits dimerization of the transcriptional activator ToxT.

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Virstatin Chemical Structure

Virstatin Chemical Structure

CAS No. : 88909-96-0

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5 mg USD 29 In-stock
10 mg USD 45 In-stock
25 mg USD 90 In-stock
50 mg USD 145 In-stock
100 mg USD 235 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Virstatin inhibits the pili system synthesis and prevents A. baumannii biofilm formation. Virstatin also inhibits dimerization of the transcriptional activator ToxT[1][2].

IC50 & Target

ToxT[1]

Molecular Weight

283.28

Formula

C16H13NO4

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N(C1=O)CCCC(O)=O)C2=CC=CC3=CC=CC1=C23

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (441.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5301 mL 17.6504 mL 35.3008 mL
5 mM 0.7060 mL 3.5301 mL 7.0602 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5301 mL 17.6504 mL 35.3008 mL 88.2519 mL
5 mM 0.7060 mL 3.5301 mL 7.0602 mL 17.6504 mL
10 mM 0.3530 mL 1.7650 mL 3.5301 mL 8.8252 mL
15 mM 0.2353 mL 1.1767 mL 2.3534 mL 5.8835 mL
20 mM 0.1765 mL 0.8825 mL 1.7650 mL 4.4126 mL
25 mM 0.1412 mL 0.7060 mL 1.4120 mL 3.5301 mL
30 mM 0.1177 mL 0.5883 mL 1.1767 mL 2.9417 mL
40 mM 0.0883 mL 0.4413 mL 0.8825 mL 2.2063 mL
50 mM 0.0706 mL 0.3530 mL 0.7060 mL 1.7650 mL
60 mM 0.0588 mL 0.2942 mL 0.5883 mL 1.4709 mL
80 mM 0.0441 mL 0.2206 mL 0.4413 mL 1.1031 mL
100 mM 0.0353 mL 0.1765 mL 0.3530 mL 0.8825 mL
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Virstatin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Virstatin
Cat. No.:
HY-127041
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