Vitamin B12-¹³C₇

Name: Vitamin B12- 13 C 7
Brand: MedChemExpress
SKU: HY-B0315S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B0315S Purity: ≥96.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Vitamin B12-¹³C₇ is the ¹³C-labeled Vitamin B12. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].

For research use only. We do not sell to patients.

Vitamin B12-<sup>13</sup>C<sub>7</sub> Chemical Structure

Vitamin B12-¹³C₇ Chemical Structure

Size	Price	Stock	Quantity
Solvent
1 μg (734.05 nM * 1 mL in Methanol)	USD 7350	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

Other Forms of Vitamin B12-¹³C₇:

Vitamin B12 In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1362.31

Formula

C₅₆¹³C₇H₈₈CoN₁₄O₁₄P

Unlabeled CAS

68-19-9

Appearance

Liquid

Color

Colorless to light yellow

SMILES

N#[C-][Co+3]123([N]4=[13CH]N(C(OC(CO)C5OP6([O-])=O)C5O)[13C]7=[13C]4[13CH]=[13C](C)[13C](C)=[13CH]7)[N]8=C9C(CCC(N)=O)C(CC(N)=O)(C)C8(C)C(C(CC(N)=O)C%10(CCC(NCC(C)O6)=O)C)[N-]1C%10=C(C)C(C(CCC(N)=O)C%11(C)C)=[N]2C%11=CC%12=[N]3C(C(CC(N)=O)(C)C%12CCC(N)=O)=C9C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, protect from light, 2 years

Solvent & Solubility

In Vitro:

DMSO : 20.83 mg/mL (15.29 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 6.25 mg/mL (4.59 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7340 mL	3.6702 mL	7.3405 mL
5 mM	0.1468 mL	0.7340 mL	1.4681 mL
10 mM	0.0734 mL	0.3670 mL	0.7340 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥96.0%

Select Batch:

Data Sheet (292 KB) SDS (251 KB)

COA (277 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. http://en.wikipedia.org/wiki/Vitamin_B12

[3]. Banerjee, R. and S.W. Ragsdale, The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem, 2003. 72: p. 209-47. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O / DMSO / DMSO	1 mM	0.7340 mL	3.6702 mL	7.3405 mL	18.3512 mL
DMSO / DMSO	5 mM	0.1468 mL	0.7340 mL	1.4681 mL	3.6702 mL
	10 mM	0.0734 mL	0.3670 mL	0.7340 mL	1.8351 mL
	15 mM	0.0489 mL	0.2447 mL	0.4894 mL	1.2234 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.