1. Anti-infection
  2. EBV
  3. VK-2019

VK-2019 is an oral active, selective EBNA1((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas.

For research use only. We do not sell to patients.

VK-2019 Chemical Structure

VK-2019 Chemical Structure

CAS No. : 2044520-06-9

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Based on 1 publication(s) in Google Scholar

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Description

VK-2019 is an oral active, selective EBNA1((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas[1].

Molecular Weight

451.51

Formula

C29H25NO4

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(C1=C(C(C#CC2=CC=C(C=C2)COC3CCOCC3)=CC=C1)C4=CC5=C(C=C4)NC=C5)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (221.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2148 mL 11.0740 mL 22.1479 mL
5 mM 0.4430 mL 2.2148 mL 4.4296 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2148 mL 11.0740 mL 22.1479 mL 55.3698 mL
5 mM 0.4430 mL 2.2148 mL 4.4296 mL 11.0740 mL
10 mM 0.2215 mL 1.1074 mL 2.2148 mL 5.5370 mL
15 mM 0.1477 mL 0.7383 mL 1.4765 mL 3.6913 mL
20 mM 0.1107 mL 0.5537 mL 1.1074 mL 2.7685 mL
25 mM 0.0886 mL 0.4430 mL 0.8859 mL 2.2148 mL
30 mM 0.0738 mL 0.3691 mL 0.7383 mL 1.8457 mL
40 mM 0.0554 mL 0.2768 mL 0.5537 mL 1.3842 mL
50 mM 0.0443 mL 0.2215 mL 0.4430 mL 1.1074 mL
60 mM 0.0369 mL 0.1846 mL 0.3691 mL 0.9228 mL
80 mM 0.0277 mL 0.1384 mL 0.2768 mL 0.6921 mL
100 mM 0.0221 mL 0.1107 mL 0.2215 mL 0.5537 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
VK-2019
Cat. No.:
HY-W725179
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