VK-2019

Cat. No.: HY-W725179 Purity: 99.97%: FAQs
Data Sheet SDS COA Handling Instructions

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VK-2019 is an oral active, selective EBNA1((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas.

For research use only. We do not sell to patients.

VK-2019 Chemical Structure

CAS No. : 2044520-06-9

Size	Price	Stock	Quantity
5 mg	USD 225	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 720	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

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Description

VK-2019 is an oral active, selective EBNA1((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas^[1].

Molecular Weight

451.51

Formula

C₂₉H₂₅NO₄

CAS No.

2044520-06-9

Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(C1=C(C(C#CC2=CC=C(C=C2)COC3CCOCC3)=CC=C1)C4=CC5=C(C=C4)NC=C5)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (221.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2148 mL	11.0740 mL	22.1479 mL
5 mM	0.4430 mL	2.2148 mL	4.4296 mL
10 mM	0.2215 mL	1.1074 mL	2.2148 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.97%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (252 KB) HNMR (269 KB) RP-HPLC (264 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. Davis MT, et al. Validation of a robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of VK-2019, a selective EBNA1 inhibitor. Biomed Chromatogr. 2024;38(2):e5775. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2148 mL	11.0740 mL	22.1479 mL	55.3698 mL
	5 mM	0.4430 mL	2.2148 mL	4.4296 mL	11.0740 mL
	10 mM	0.2215 mL	1.1074 mL	2.2148 mL	5.5370 mL
	15 mM	0.1477 mL	0.7383 mL	1.4765 mL	3.6913 mL
	20 mM	0.1107 mL	0.5537 mL	1.1074 mL	2.7685 mL
	25 mM	0.0886 mL	0.4430 mL	0.8859 mL	2.2148 mL
	30 mM	0.0738 mL	0.3691 mL	0.7383 mL	1.8457 mL
	40 mM	0.0554 mL	0.2768 mL	0.5537 mL	1.3842 mL
	50 mM	0.0443 mL	0.2215 mL	0.4430 mL	1.1074 mL
	60 mM	0.0369 mL	0.1846 mL	0.3691 mL	0.9228 mL
	80 mM	0.0277 mL	0.1384 mL	0.2768 mL	0.6921 mL
	100 mM	0.0221 mL	0.1107 mL	0.2215 mL	0.5537 mL

VK-2019 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VK-20192044520-06-9VK2019VK 2019EBVEpstein-Barr VirusEBV-associated carcinomasInhibitorinhibitorinhibit

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