2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. vMIP-II (1-21)

vMIP-II (1-21)  (Synonyms: NT21MP; V1 peptide)

Cat. No.: HY-P4109
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vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM).

For research use only. We do not sell to patients.

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vMIP-II (1-21) Chemical Structure

vMIP-II (1-21) Chemical Structure

CAS No. : 265650-93-9

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Other Forms of vMIP-II (1-21):

vMIP-II (1-21) Related Antibodies

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Description

vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM)[1].

In Vitro

vMIP-II (1-21) (0.01-10 μM) binds with CXCR4[1].
vMIP-II (1-21) (25-200 μM) inhibits CXCR4 mediates T- and dual-tropic HIV-1 gp120-mediated cell-cell fusion[1].
vMIP-II (1-21) (100 μM) dose-dependently inhibits the chemotactic activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

vMIP-II (1-21) Related Antibodies
Molecular Weight

2425.84

Formula

C108H169N33O27S
CAS No.
Sequence

Leu-Gly-Ala-Ser-Trp-His-Arg-Pro-Asp-Lys-Cys-Cys-Leu-Gly-Tyr-Gln-Lys-Arg-Pro-Leu-Pro
Sequence Shortening

LGASWHRPDKCCLGYQKRPLP
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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vMIP-II (1-21) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

vMIP-II (1-21)265650-93-9NT21MP V1 peptideCXCRCXC chemokine receptorsC-X-C motif chemokine receptorspeptide fragmentvMIP-IIcell fusionHIV-1Inhibitorinhibitorinhibit

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