2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. vMIP-II (1-21) TFA

vMIP-II (1-21) TFA  (Synonyms: NT21MP TFA; V1 peptide TFA)

Cat. No.: HY-P4109A
Handling Instructions

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vMIP-II (1-21) (NT21MP) TFA is an inhibitor of CXCR4. vMIP-II (1-21) TFA interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) TFA inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM).

For research use only. We do not sell to patients.

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vMIP-II (1-21) TFA Chemical Structure

vMIP-II (1-21) TFA Chemical Structure

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5 mg USD 175 In-stock
10 mg USD 280 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of vMIP-II (1-21) TFA:

vMIP-II (1-21) TFA Related Antibodies

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CXCR CXCR1 CXCR2 CXCR3 CXCR4 CXCR7 CXCR6

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Description

vMIP-II (1-21) (NT21MP) TFA is an inhibitor of CXCR4. vMIP-II (1-21) TFA interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) TFA inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM)[1].

Molecular Weight

2425.84 (free base)

Formula

C108H169N33O27S.xC2HF3O2
Appearance

Solid

Sequence

Leu-Gly-Ala-Ser-Trp-His-Arg-Pro-Asp-Lys-Cys-Cys-Leu-Gly-Tyr-Gln-Lys-Arg-Pro-Leu-Pro
Sequence Shortening

LGASWHRPDKCCLGYQKRPLP
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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vMIP-II (1-21) TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

vMIP-II (1-21)NT21MPV1 peptideCXCRCXC chemokine receptorsC-X-C motif chemokine receptorspeptide fragmentvMIP-IIcell fusionHIV-1Inhibitorinhibitorinhibit

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