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VUANT1 (VU0183254) is an allosteric antagonist of insect odorant receptor ion channels, which has the activity of inhibiting insect odorant receptor signaling. VUANT1 can inhibit the activation of insect odorant receptors through allosteric regulation, which is important for the study of the molecular mechanism of insect olfactory signaling. Although it may be of limited use in insect control programs, it can be used as a pharmacological tool to study related mechanisms.

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VUANT1 Chemical Structure

VUANT1 Chemical Structure

CAS No. : 663212-40-6

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5 mg USD 30 In-stock
10 mg USD 45 In-stock
25 mg USD 88 In-stock
50 mg USD 140 In-stock
100 mg USD 225 In-stock
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VUANT1 Related Antibodies

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Description

VUANT1 (VU0183254) is an allosteric antagonist of insect odorant receptor ion channels, which has the activity of inhibiting insect odorant receptor signaling. VUANT1 can inhibit the activation of insect odorant receptors through allosteric regulation, which is important for the study of the molecular mechanism of insect olfactory signaling. Although it may be of limited use in insect control programs, it can be used as a pharmacological tool to study related mechanisms.

Molecular Weight

434.53

Formula

C22H18N4O2S2
CAS No.
Appearance

Solid

SMILES

CCN1C(SCC(N2C3=C(SC4=CC=CC=C24)C=CC=C3)=O)=NN=C1C5=CC=CO5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (191.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3013 mL 11.5067 mL 23.0134 mL
5 mM 0.4603 mL 2.3013 mL 4.6027 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3013 mL 11.5067 mL 23.0134 mL 57.5334 mL
5 mM 0.4603 mL 2.3013 mL 4.6027 mL 11.5067 mL
10 mM 0.2301 mL 1.1507 mL 2.3013 mL 5.7533 mL
15 mM 0.1534 mL 0.7671 mL 1.5342 mL 3.8356 mL
20 mM 0.1151 mL 0.5753 mL 1.1507 mL 2.8767 mL
25 mM 0.0921 mL 0.4603 mL 0.9205 mL 2.3013 mL
30 mM 0.0767 mL 0.3836 mL 0.7671 mL 1.9178 mL
40 mM 0.0575 mL 0.2877 mL 0.5753 mL 1.4383 mL
50 mM 0.0460 mL 0.2301 mL 0.4603 mL 1.1507 mL
60 mM 0.0384 mL 0.1918 mL 0.3836 mL 0.9589 mL
80 mM 0.0288 mL 0.1438 mL 0.2877 mL 0.7192 mL
100 mM 0.0230 mL 0.1151 mL 0.2301 mL 0.5753 mL
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VUANT1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VUANT1663212-40-6VU0183254VUANT 1VUANT-1VU 0183254VU-0183254OthersInhibitorinhibitorinhibit

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