1. Membrane Transporter/Ion Channel
  2. Calmodulin
  3. W-7 isomer hydrochloride

W-7 isomer hydrochloride is an isomer of W-7 hydrochloride (HY-100912). W-7 hydrochloride is a selective calmodulin antagonist.

For research use only. We do not sell to patients.

W-7 isomer hydrochloride Chemical Structure

W-7 isomer hydrochloride Chemical Structure

CAS No. : 69762-85-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 132 In-stock
Solution
10 mM * 1 mL in DMSO USD 132 In-stock
Solid
1 mg USD 57 In-stock
5 mg USD 120 In-stock
10 mg USD 200 In-stock
25 mg USD 390 In-stock
50 mg USD 600 In-stock
100 mg USD 900 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of W-7 isomer hydrochloride:

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Description

W-7 isomer hydrochloride is an isomer of W-7 hydrochloride (HY-100912). W-7 hydrochloride is a selective calmodulin antagonist[1].

Molecular Weight

377.33

Formula

C16H22Cl2N2O2S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C2C(Cl)=CC=CC2=C1)(NCCCCCCN)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (662.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 20.83 mg/mL (55.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6502 mL 13.2510 mL 26.5020 mL
5 mM 0.5300 mL 2.6502 mL 5.3004 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.6502 mL 13.2510 mL 26.5020 mL 66.2550 mL
5 mM 0.5300 mL 2.6502 mL 5.3004 mL 13.2510 mL
10 mM 0.2650 mL 1.3251 mL 2.6502 mL 6.6255 mL
15 mM 0.1767 mL 0.8834 mL 1.7668 mL 4.4170 mL
20 mM 0.1325 mL 0.6626 mL 1.3251 mL 3.3128 mL
25 mM 0.1060 mL 0.5300 mL 1.0601 mL 2.6502 mL
30 mM 0.0883 mL 0.4417 mL 0.8834 mL 2.2085 mL
40 mM 0.0663 mL 0.3313 mL 0.6626 mL 1.6564 mL
50 mM 0.0530 mL 0.2650 mL 0.5300 mL 1.3251 mL
DMSO 60 mM 0.0442 mL 0.2209 mL 0.4417 mL 1.1043 mL
80 mM 0.0331 mL 0.1656 mL 0.3313 mL 0.8282 mL
100 mM 0.0265 mL 0.1325 mL 0.2650 mL 0.6626 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
W-7 isomer hydrochloride
Cat. No.:
HY-100913
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