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WAY-612453 is an active molecule for the study of amyloid diseases and synucleinopathies.

For research use only. We do not sell to patients.

WAY-612453 Chemical Structure

WAY-612453 Chemical Structure

CAS No. : 300809-10-3

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5 mg USD 45 In-stock
10 mg USD 70 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

WAY-612453 is an active molecule for the study of amyloid diseases and synucleinopathies.

Molecular Weight

275.16

Formula

C9H8Cl2N4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN1N=NN=C1SCC2=C(Cl)C=CC=C2Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (363.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6342 mL 18.1712 mL 36.3425 mL
5 mM 0.7268 mL 3.6342 mL 7.2685 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (251 KB) HNMR (281 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6342 mL 18.1712 mL 36.3425 mL 90.8562 mL
5 mM 0.7268 mL 3.6342 mL 7.2685 mL 18.1712 mL
10 mM 0.3634 mL 1.8171 mL 3.6342 mL 9.0856 mL
15 mM 0.2423 mL 1.2114 mL 2.4228 mL 6.0571 mL
20 mM 0.1817 mL 0.9086 mL 1.8171 mL 4.5428 mL
25 mM 0.1454 mL 0.7268 mL 1.4537 mL 3.6342 mL
30 mM 0.1211 mL 0.6057 mL 1.2114 mL 3.0285 mL
40 mM 0.0909 mL 0.4543 mL 0.9086 mL 2.2714 mL
50 mM 0.0727 mL 0.3634 mL 0.7268 mL 1.8171 mL
60 mM 0.0606 mL 0.3029 mL 0.6057 mL 1.5143 mL
80 mM 0.0454 mL 0.2271 mL 0.4543 mL 1.1357 mL
100 mM 0.0363 mL 0.1817 mL 0.3634 mL 0.9086 mL
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WAY-612453 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WAY-612453300809-10-3WAY612453WAY 612453OthersInhibitorinhibitorinhibit

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