2. Neuronal Signaling
  3. Monoamine Oxidase
  4. WAY-620147

WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide derivative that inhibits monoamine oxidase (Monoamine Oxidase). WAY-620147 inhibits MAO-A and MAO-B with IC50s of 26 μM and 55 μM, respectively.

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WAY-620147 Chemical Structure

WAY-620147 Chemical Structure

CAS No. : 515866-67-8

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WAY-620147 Related Antibodies

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MAO-A MAO-B

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Description

WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide derivative that inhibits monoamine oxidase (Monoamine Oxidase). WAY-620147 inhibits MAO-A and MAO-B with IC50s of 26 μM and 55 μM, respectively[1].

IC50 & Target

IC50: 26 μM (MAO-A), 55 μM (MAO-B)[1]
Molecular Weight

314.18

Formula

C12H16BrN3O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C1COCCN1CCNC(=O)C2=CC(=CN=C2)Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (318.29 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1829 mL 15.9144 mL 31.8289 mL
5 mM 0.6366 mL 3.1829 mL 6.3658 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1829 mL 15.9144 mL 31.8289 mL 79.5722 mL
5 mM 0.6366 mL 3.1829 mL 6.3658 mL 15.9144 mL
10 mM 0.3183 mL 1.5914 mL 3.1829 mL 7.9572 mL
15 mM 0.2122 mL 1.0610 mL 2.1219 mL 5.3048 mL
20 mM 0.1591 mL 0.7957 mL 1.5914 mL 3.9786 mL
25 mM 0.1273 mL 0.6366 mL 1.2732 mL 3.1829 mL
30 mM 0.1061 mL 0.5305 mL 1.0610 mL 2.6524 mL
40 mM 0.0796 mL 0.3979 mL 0.7957 mL 1.9893 mL
50 mM 0.0637 mL 0.3183 mL 0.6366 mL 1.5914 mL
60 mM 0.0530 mL 0.2652 mL 0.5305 mL 1.3262 mL
80 mM 0.0398 mL 0.1989 mL 0.3979 mL 0.9947 mL
100 mM 0.0318 mL 0.1591 mL 0.3183 mL 0.7957 mL
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WAY-620147 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WAY-620147515866-67-8WAY620147WAY 620147Monoamine OxidaseMAOInhibitorinhibitorinhibit

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