Withaphysalin E

Cat. No.: HY-N12690 Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Withaphysalin E is a natural product that can be isolated from Physalis divericata. Withaphysalin E can be used in the study of non-small cell lung cancer.

For research use only. We do not sell to patients.

Withaphysalin E Chemical Structure

CAS No. : 118985-24-3

Size	Price	Stock	Quantity
500 μg	USD 320	In-stock	Estimated Time of Arrival: December 31
1 mg	USD 530	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Purity & Documentation
References
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Description

Withaphysalin E is a natural product that can be isolated from Physalis divericata. Withaphysalin E can be used in the study of non-small cell lung cancer^[1]^[2].

Molecular Weight

482.57

Formula

C₂₈H₃₄O₇

CAS No.

118985-24-3

Appearance

Solid

Color

White to off-white

SMILES

O[C@@]12[C@](C(O3)=O)(CC[C@@]([C@@]4(C5=CC=CC4=O)C)([H])[C@@]1([H])C[C@H]5O)[C@@](CC2)([H])[C@@]3([C@@](OC6=O)([H])CC(C)=C6C)C

Structure Classification

Steroids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 15 mg/mL (31.08 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0722 mL	10.3612 mL	20.7224 mL
5 mM	0.4144 mL	2.0722 mL	4.1445 mL
10 mM	0.2072 mL	1.0361 mL	2.0722 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (277 KB) SDS (251 KB)

COA (258 KB)

Handling Instructions (2659 KB)

References

[1]. Rao PC, et al. Cytotoxicity of withasteroids: withametelin induces cell cycle arrest at G2/M phase and mitochondria-mediated apoptosis in non-small cell lung cancer A549 cells. Tumour Biol. 2016 Sep;37(9):12579-12587. [Content Brief]

[2]. Ma L, et al. Withaphysanolide A, a novel C-27 norwithanolide skeleton, and other cytotoxic compounds from Physalis divericata. Tetrahedron letters, 2007, 48(3): 449-452

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0722 mL	10.3612 mL	20.7224 mL	51.8060 mL
	5 mM	0.4144 mL	2.0722 mL	4.1445 mL	10.3612 mL
	10 mM	0.2072 mL	1.0361 mL	2.0722 mL	5.1806 mL
	15 mM	0.1381 mL	0.6907 mL	1.3815 mL	3.4537 mL
	20 mM	0.1036 mL	0.5181 mL	1.0361 mL	2.5903 mL
	25 mM	0.0829 mL	0.4144 mL	0.8289 mL	2.0722 mL
	30 mM	0.0691 mL	0.3454 mL	0.6907 mL	1.7269 mL

Withaphysalin E Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Withaphysalin E118985-24-3OthersHCT-116NCI-H460Natural ProductInhibitorinhibitorinhibit

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