2. Neuronal Signaling
  3. Transthyretin (TTR)
  4. WT-TTR inhibitor 1

WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM.

For research use only. We do not sell to patients.

WT-TTR inhibitor 1 Chemical Structure

WT-TTR inhibitor 1 Chemical Structure

CAS No. : 23983-05-3

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10 mg USD 130 In-stock
25 mg USD 250 In-stock
50 mg USD 400 In-stock
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Based on 1 publication(s) in Google Scholar

WT-TTR inhibitor 1 Related Antibodies

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Description

WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].

Molecular Weight

312.77

Formula

C16H9ClN2OS
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1/C(SC2=NC3=C(N21)C=CC=C3)=C/C4=C(Cl)C=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 4.76 mg/mL (15.22 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1972 mL 15.9862 mL 31.9724 mL
5 mM 0.6394 mL 3.1972 mL 6.3945 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1972 mL 15.9862 mL 31.9724 mL 79.9309 mL
5 mM 0.6394 mL 3.1972 mL 6.3945 mL 15.9862 mL
10 mM 0.3197 mL 1.5986 mL 3.1972 mL 7.9931 mL
15 mM 0.2131 mL 1.0657 mL 2.1315 mL 5.3287 mL
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WT-TTR inhibitor 1 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WT-TTR inhibitor 123983-05-3Transthyretin (TTR)thyroxine-binding prealbuminInhibitorinhibitorinhibit

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