2. JAK/STAT Signaling Stem Cell/Wnt
  3. STAT
  4. WZ-2-033

WZ-2-033 is a potent STAT3 inhibitor. WZ-2-033 inhibits MDA-MB-231, HCC70, and MDA-MB231-4175 cells proliferation, colony survival, migration, and invasion with IC50s of 0.7, 1.3, and 1.3 μM, respectively.

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WZ-2-033 Chemical Structure

WZ-2-033 Chemical Structure

CAS No. : 2416196-47-7

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WZ-2-033 Related Antibodies

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Description

WZ-2-033 is a potent STAT3 inhibitor. WZ-2-033 inhibits MDA-MB-231, HCC70, and MDA-MB231-4175 cells proliferation, colony survival, migration, and invasion with IC50s of 0.7, 1.3, and 1.3 μM, respectively[1].

Molecular Weight

513.49

Formula

C25H18F3N3O4S
CAS No.
SMILES

O=C(CC1=C(C2=CC=C(C(F)(F)F)C=C2)N=C3C=C(C=CN31)OC)NC4=CC5=C(C=CS(=O)5=O)C=C4
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WZ-2-033 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WZ-2-0332416196-47-7STAThuman triple-negative breast cancergastric cancer xenograftsTNBCInhibitorinhibitorinhibit

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