XMD-17-51

Cat. No.: HY-117291: FAQs
Data Sheet Handling Instructions

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XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (XMD-17-51 TFA) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

XMD-17-51 Chemical Structure

CAS No. : 1628614-50-5

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Other In-stock Forms of XMD-17-51:

XMD-17-51 TFA

Other Forms of XMD-17-51:

XMD-17-51 TFA In-stock

1 Publications Citing Use of MCE XMD-17-51

•Front Pharmacol. 2021 Mar 8;12:603453. [Abstract]

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Biological Activity
Purity & Documentation
References
Customer Review

Description	XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases^[1].
In Vitro	XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), polo kinase 1, 2, 3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK, ULK2, PLK, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and can be used in the treatment of various diseases, disorders or conditions^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. XMD-17-51 Related Antibodies
Molecular Weight	404.47
Formula	C₂₁H₂₄N₈O
CAS No.	1628614-50-5
SMILES	O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. WO 2014145909 A2.

XMD-17-51 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XMD-17-511628614-50-5OthersInhibitorinhibitorinhibit

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