2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Xylometazoline

Xylometazoline is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline can constrict nasal blood vessels and increase nasal airflow. Xylometazoline can be used in nose stuffiness and runny nose research.

For research use only. We do not sell to patients.

Xylometazoline Chemical Structure

Xylometazoline Chemical Structure

CAS No. : 526-36-3

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Xylometazoline Related Antibodies

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Description

Xylometazoline is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline can constrict nasal blood vessels and increase nasal airflow. Xylometazoline can be used in nose stuffiness and runny nose research[1][2].

IC50 & Target[2]

Alpha-1A adrenergic receptor

0.05 μM (Ki)

Alpha-1B adrenergic receptor

0.30 μM (Ki)

Alpha-1D adrenergic receptor

0.15 μM (Ki)

Alpha-2A adrenergic receptor

0.88 μM (Ki)

Alpha-2B adrenergic receptor

1.7 μM (Ki)

Alpha-2C adrenergic receptor

0.19 μM (Ki)

Molecular Weight

244.38

Formula

C16H24N2
CAS No.
SMILES

CC1=C(CC2=NCCN2)C(C)=CC(C(C)(C)C)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Xylometazoline Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xylometazoline526-36-3Adrenergic ReceptorBeta Receptorconstrict nasal blood vesselsincrease nasal airflownose stuffinessrunny noseInhibitorinhibitorinhibit

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