2. Epigenetics
  3. Histone Acetyltransferase
  4. YEATS4-IN-1

YEATS4-IN-1 (Compound 4d) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a Ki value of 33 nM.

For research use only. We do not sell to patients.

YEATS4-IN-1 Chemical Structure

YEATS4-IN-1 Chemical Structure

CAS No. : 3034365-92-6

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YEATS4-IN-1 Related Antibodies

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Description

YEATS4-IN-1 (Compound 4d) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a Ki value of 33 nM[1].

In Vivo

The pharmacokinetic parameters of NAMPT degrader-3(4d)(p.o., 100 mg/kg) in mice

4d T1/2 (h) AUC(ng*min/mL) Tmax (h) Cmas (ng/mL)
1.2 24700 0.5 9140

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

412.57

Formula

C24H36N4O2
CAS No.
SMILES

OC1(CN2C[C@H](C)[C@@H](C3=C(C=CC(C(NCC)=O)=C4)N4N=C3C)CC2)CCCCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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YEATS4-IN-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YEATS4-IN-13034365-92-6Histone AcetyltransferaseHATsHATYEATS4binderKAcInhibitorinhibitorinhibit

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