2. PROTAC Cell Cycle/DNA Damage Autophagy Apoptosis Immunology/Inflammation Epigenetics
  3. PROTACs FKBP Epigenetic Reader Domain
  4. YT117R

YT117R is a PROTAC degrader of FKBP12 and Pink: Target protein ligand: (HY-158301); Black: linker (HY-42776); Blue: E3 ligase ligand (HY-78695)).

For research use only. We do not sell to patients.

YT117R Chemical Structure

YT117R Chemical Structure

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YT117R Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

YT117R is a PROTAC degrader of FKBP12 and Pink: Target protein ligand: (HY-158301); Black: linker (HY-42776); Blue: E3 ligase ligand (HY-78695))[1].

Molecular Weight

958.52

Formula

C50H52ClN9O7S
SMILES

C=CC(N1C[C@@H]([C@@H]1C(NC2=CC=CC3=C2N=CC=C3)=O)C4=CC=C(C=C4)C(NCCOCCOCCOCCNC(C[C@@H]5N=C(C6=C(N7C(C)=NN=C57)SC(C)=C6C)C8=CC=C(C=C8)Cl)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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YT117R Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YT117RPROTACsFKBPEpigenetic Reader DomainFK506-binding proteinFKBP12BRD4DegraderInhibitorinhibitorinhibit

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HY-169148
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