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YTHDC1-IN-1 (compound 40) is a potent inhibitor of YTHDC1, with the Kd of 49 nM. YTHDC1-IN-1 plays an important role in cancer research.

For research use only. We do not sell to patients.

YTHDC1-IN-1 Chemical Structure

YTHDC1-IN-1 Chemical Structure

CAS No. : 2995344-53-9

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5 mg USD 485 In-stock
10 mg USD 780 In-stock
25 mg USD 1560 In-stock
50 mg USD 2500 In-stock
100 mg USD 4000 In-stock
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Based on 1 publication(s) in Google Scholar

YTHDC1-IN-1 Related Antibodies

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Description

YTHDC1-IN-1 (compound 40) is a potent inhibitor of YTHDC1, with the Kd of 49 nM. YTHDC1-IN-1 plays an important role in cancer research[1].

Molecular Weight

308.17

Formula

C13H11Cl2N5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CNC1=NC(Cl)=NC2=C(CC3=CC=CC(Cl)=C3)NN=C21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (81.12 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2450 mL 16.2248 mL 32.4496 mL
5 mM 0.6490 mL 3.2450 mL 6.4899 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.44%

COA (254 KB) HNMR (250 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2450 mL 16.2248 mL 32.4496 mL 81.1241 mL
5 mM 0.6490 mL 3.2450 mL 6.4899 mL 16.2248 mL
10 mM 0.3245 mL 1.6225 mL 3.2450 mL 8.1124 mL
15 mM 0.2163 mL 1.0817 mL 2.1633 mL 5.4083 mL
20 mM 0.1622 mL 0.8112 mL 1.6225 mL 4.0562 mL
25 mM 0.1298 mL 0.6490 mL 1.2980 mL 3.2450 mL
30 mM 0.1082 mL 0.5408 mL 1.0817 mL 2.7041 mL
40 mM 0.0811 mL 0.4056 mL 0.8112 mL 2.0281 mL
50 mM 0.0649 mL 0.3245 mL 0.6490 mL 1.6225 mL
60 mM 0.0541 mL 0.2704 mL 0.5408 mL 1.3521 mL
80 mM 0.0406 mL 0.2028 mL 0.4056 mL 1.0141 mL
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YTHDC1-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YTHDC1-IN-12995344-53-9OthersTHP-A cellsAML cell lineInhibitorinhibitorinhibit

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