(Z)-Guggulsterone (Standard)

Cat. No.: HY-110066R Purity: ≥98%: FAQs
Handling Instructions

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(Z)-Guggulsterone (Standard) is the analytical standard of (Z)-Guggulsterone. This product is intended for research and analytical applications. (Z)-Guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis. (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection.

For research use only. We do not sell to patients.

(Z)-Guggulsterone (Standard) Chemical Structure

CAS No. : 39025-23-5

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Description	(Z)-Guggulsterone (Standard) is the analytical standard of (Z)-Guggulsterone . This product is intended for research and analytical applications. (Z)-Guggulsterone , a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis. (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection.
Molecular Weight	312.45
Formula	C₂₁H₂₈O₂
CAS No.	39025-23-5
SMILES	C[C@@]1(/C2=C/C)[C@](CC2=O)([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])CC1.[Z]
Structure Classification	Steroids
Initial Source	Plants Burseraceae Commiphora myrrha (Nees) Engl.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

(Z)-Guggulsterone (Standard) Related Classifications

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Z)-Guggulsterone (Standard)39025-23-5ApoptosisVEGFRAktAngiotensin-converting Enzyme (ACE)SARS-CoVFXRVascular endothelial growth factor receptorPKBProtein kinase BSARS coronavirusNR1H4Inhibitorinhibitorinhibit

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