2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. Zilovertamab

Zilovertamab  (Synonyms: UC-961; Cirmtuzumab)

Cat. No.: HY-P99201 Purity: 98.20%
COA

Molarity Calculator

Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling.

For research use only. We do not sell to patients.

Size Price Stock Quantity
1 mg USD 300 In-stock
5 mg USD 850 In-stock
10 mg USD 1350 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Zilovertamab Related Antibodies

Top Publications Citing Use of Products

View All ROR Isoform Specific Products:

View All Isoforms
RORγ RORα RORβ

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Humanized
In Vitro

Zilovertamab (25 and 50 μg/mL; 72 h) inhibits high-grade serous ovarian cancer (HGSOC) cell proliferation[1].
Zilovertamab (50 μg/mL; 72 h) down-regulates ROR1 expression levels in CaOV3 at the transcriptional level[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Zilovertamab Related Antibodies

Cell Proliferation Assay[1]

Cell Line: CaOV3, CaOV3CisR, PEO1, and PEO4 cells
Concentration: 25 and 50 µg/mL
Incubation Time: 72 hours
Result: Reduced the proliferation of CaOV3, CaOV3CisR and PEO1.

Western Blot Analysis[1]

Cell Line: CaOV3, CaOV3CisR, PEO1, and PEO4 cells
Concentration: 50 µg/mL
Incubation Time: 72 hours
Result: Down-regulated ROR1 expression levels in CaOV3 at the transcriptional level.
Clinical Trial
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Zilovertamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Purity & Documentation

Purity: 98.20%

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Zilovertamab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZilovertamabUC-961 CirmtuzumabUC961UC 961RORRAR-related orphan receptorhumanised monoclonal antibodyWnt5aROR1 signallingCaOV3Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Zilovertamab
Cat. No.:
HY-P99201
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.