2. Metabolic Enzyme/Protease Autophagy
  3. PGC-1α Autophagy
  4. ZLN005-d4

ZLN005-d4 is deuterium labeled ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)[1].

For research use only. We do not sell to patients.

ZLN005-d<sub>4</sub> Chemical Structure

ZLN005-d4 Chemical Structure

CAS No. : 2410443-42-2

Size Price Stock Quantity
1 mg USD 300 In-stock
5 mg USD 650 In-stock
10 mg USD 1100 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of ZLN005-d4:

ZLN005-d4 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

ZLN005-d4 is deuterium labeled ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ZLN005-d4 Related Antibodies
Molecular Weight

254.36

Formula

C17H14D4N2
CAS No.
Unlabeled CAS

49671-76-3
Appearance

Solid

Color

White to off-white

SMILES

CC(C)(C1=CC=C(C=C1)C2=NC3=C([2H])C([2H])=C([2H])C([2H])=C3N2)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 22 mg/mL (86.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 22 mg/mL (86.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9314 mL 19.6572 mL 39.3144 mL
5 mM 0.7863 mL 3.9314 mL 7.8629 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 3.9314 mL 19.6572 mL 39.3144 mL 98.2859 mL
5 mM 0.7863 mL 3.9314 mL 7.8629 mL 19.6572 mL
10 mM 0.3931 mL 1.9657 mL 3.9314 mL 9.8286 mL
15 mM 0.2621 mL 1.3105 mL 2.6210 mL 6.5524 mL
20 mM 0.1966 mL 0.9829 mL 1.9657 mL 4.9143 mL
25 mM 0.1573 mL 0.7863 mL 1.5726 mL 3.9314 mL
30 mM 0.1310 mL 0.6552 mL 1.3105 mL 3.2762 mL
40 mM 0.0983 mL 0.4914 mL 0.9829 mL 2.4571 mL
50 mM 0.0786 mL 0.3931 mL 0.7863 mL 1.9657 mL
60 mM 0.0655 mL 0.3276 mL 0.6552 mL 1.6381 mL
80 mM 0.0491 mL 0.2457 mL 0.4914 mL 1.2286 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

ZLN005-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZLN005-d42410443-42-2PGC-1αAutophagyPPARγ coactivator-1αInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
ZLN005-d4
Cat. No.:
HY-17538S
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.