2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. ZM226600

ZM226600 is an ATP-sensitive potassium channel opener (EC50: 500 nM). ZM226600 inhibits bladder spontaneous activity.

For research use only. We do not sell to patients.

ZM226600 Chemical Structure

ZM226600 Chemical Structure

CAS No. : 147695-92-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 104 In-stock
Solution
10 mM * 1 mL in DMSO USD 104 In-stock
Solid
5 mg USD 95 In-stock
10 mg USD 150 In-stock
25 mg USD 300 In-stock
50 mg USD 480 In-stock
100 mg USD 750 In-stock
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Based on 1 publication(s) in Google Scholar

ZM226600 Related Antibodies

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Description

ZM226600 is an ATP-sensitive potassium channel opener (EC50: 500 nM). ZM226600 inhibits bladder spontaneous activity[1][2].

In Vitro

ZM226600 (1 μM, 30 min) inhibits bladder spontaneous activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ZM226600 Related Antibodies
In Vivo

ZM226600 (10-1000 nmol/kg, i.v.) does not alter significantly the heart beats rate in anaesthetized rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

373.35

Formula

C16H14F3NO4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=CC=C(S(=O)(C2=CC=CC=C2)=O)C=C1)C(C)(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (669.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6785 mL 13.3923 mL 26.7845 mL
5 mM 0.5357 mL 2.6785 mL 5.3569 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6785 mL 13.3923 mL 26.7845 mL 66.9613 mL
5 mM 0.5357 mL 2.6785 mL 5.3569 mL 13.3923 mL
10 mM 0.2678 mL 1.3392 mL 2.6785 mL 6.6961 mL
15 mM 0.1786 mL 0.8928 mL 1.7856 mL 4.4641 mL
20 mM 0.1339 mL 0.6696 mL 1.3392 mL 3.3481 mL
25 mM 0.1071 mL 0.5357 mL 1.0714 mL 2.6785 mL
30 mM 0.0893 mL 0.4464 mL 0.8928 mL 2.2320 mL
40 mM 0.0670 mL 0.3348 mL 0.6696 mL 1.6740 mL
50 mM 0.0536 mL 0.2678 mL 0.5357 mL 1.3392 mL
60 mM 0.0446 mL 0.2232 mL 0.4464 mL 1.1160 mL
80 mM 0.0335 mL 0.1674 mL 0.3348 mL 0.8370 mL
100 mM 0.0268 mL 0.1339 mL 0.2678 mL 0.6696 mL
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ZM226600 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZM226600147695-92-9ZM 226600ZM-226600Potassium ChannelKcsAK+ channelbladderInhibitorinhibitorinhibit

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