2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel Neuronal Signaling
  3. Drug Metabolite GABA Receptor
  4. Zopiclone N-oxide

Zopiclone N-oxide (RP 29753) is a less active metabolite of Zopiclone. Zopiclone N-oxide is also an impurity of Eszopiclone and is formed by the oxidation of Eszopiclone.

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Zopiclone N-oxide Chemical Structure

Zopiclone N-oxide Chemical Structure

CAS No. : 43200-96-0

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Zopiclone N-oxide Related Antibodies

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Description

Zopiclone N-oxide (RP 29753) is a less active metabolite of Zopiclone. Zopiclone N-oxide is also an impurity of Eszopiclone and is formed by the oxidation of Eszopiclone[1][2].

Molecular Weight

404.81

Formula

C17H17ClN6O4
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(N1CC[N+](C)([O-])CC1)OC2N(C3=NC=C(Cl)C=C3)C(C4=NC=CN=C42)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (41.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4703 mL 12.3515 mL 24.7029 mL
5 mM 0.4941 mL 2.4703 mL 4.9406 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4703 mL 12.3515 mL 24.7029 mL 61.7574 mL
5 mM 0.4941 mL 2.4703 mL 4.9406 mL 12.3515 mL
10 mM 0.2470 mL 1.2351 mL 2.4703 mL 6.1757 mL
15 mM 0.1647 mL 0.8234 mL 1.6469 mL 4.1172 mL
20 mM 0.1235 mL 0.6176 mL 1.2351 mL 3.0879 mL
25 mM 0.0988 mL 0.4941 mL 0.9881 mL 2.4703 mL
30 mM 0.0823 mL 0.4117 mL 0.8234 mL 2.0586 mL
40 mM 0.0618 mL 0.3088 mL 0.6176 mL 1.5439 mL
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Zopiclone N-oxide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zopiclone N-oxide43200-96-0RP 29753RP29753RP-29753Drug MetaboliteGABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorZopiclonemetaboliteEszopicloneInhibitorinhibitorinhibit

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