2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Zuvotolimod

Zuvotolimod is a myeloid cell agonist compound-linker for antibody conjugate. Zuvotolimod can be used in the research of cancer and hepatitis.

For research use only. We do not sell to patients.

Zuvotolimod Chemical Structure

Zuvotolimod Chemical Structure

CAS No. : 2355262-97-2

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1 mg USD 880 In-stock
5 mg USD 2200 In-stock
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Based on 1 publication(s) in Google Scholar

Zuvotolimod Related Antibodies

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Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

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  • Purity & Documentation

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  • Customer Review

Description

Zuvotolimod is a myeloid cell agonist compound-linker for antibody conjugate. Zuvotolimod can be used in the research of cancer and hepatitis[1][2].

Molecular Weight

1059.22

Formula

C55H70N12O10
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CC(C=C(NC(C2=CC3=C(C=C(C(N(CCC)CCC)=O)CC(N)=N3)C=C2)=O)C=N4)=C4CC1)OCC5=CC=C(NC([C@](NC([C@@](C(C)C)([H])NC(CCCCCN6C(C=CC6=O)=O)=O)=O)([H])CCCNC(N)=O)=O)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (94.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9441 mL 4.7205 mL 9.4409 mL
5 mM 0.1888 mL 0.9441 mL 1.8882 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9441 mL 4.7205 mL 9.4409 mL 23.6023 mL
5 mM 0.1888 mL 0.9441 mL 1.8882 mL 4.7205 mL
10 mM 0.0944 mL 0.4720 mL 0.9441 mL 2.3602 mL
15 mM 0.0629 mL 0.3147 mL 0.6294 mL 1.5735 mL
20 mM 0.0472 mL 0.2360 mL 0.4720 mL 1.1801 mL
25 mM 0.0378 mL 0.1888 mL 0.3776 mL 0.9441 mL
30 mM 0.0315 mL 0.1573 mL 0.3147 mL 0.7867 mL
40 mM 0.0236 mL 0.1180 mL 0.2360 mL 0.5901 mL
50 mM 0.0189 mL 0.0944 mL 0.1888 mL 0.4720 mL
60 mM 0.0157 mL 0.0787 mL 0.1573 mL 0.3934 mL
80 mM 0.0118 mL 0.0590 mL 0.1180 mL 0.2950 mL
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Zuvotolimod Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zuvotolimod2355262-97-2ADC LinkerAntibody-drug conjugates linkercancerhepatitiscompound-linkermyeloid cellantibody conjugateInhibitorinhibitorinhibit

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