2. Metabolic Enzyme/Protease
  3. Amylases Glycosidase
  4. α-Amylase/α-Glucosidase-IN-11

α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier.

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α-Amylase/α-Glucosidase-IN-11 Chemical Structure

α-Amylase/α-Glucosidase-IN-11 Chemical Structure

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Description

α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier[1].

Molecular Weight

622.15

Formula

C33H40ClN5O5
SMILES

O=C(N/N=C1C(NC2=C\1C=CC=C2Cl)=O)COC3=C(C)C=CC=C3C[C@@H]4C[C@]5([H])N([C@]6(N(C)C5=O)[C@H](C(C)C)CC[C@@H](C)C6)O4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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α-Amylase/α-Glucosidase-IN-11 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

α-Amylase/α-Glucosidase-IN-11AmylasesGlycosidaseAntidiabetic agentsIsoxazolidine-isatin hybridsDrug-likenessInhibitorinhibitorinhibit

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