α-Cholestane-d₄

Name: α-Cholestane-d 4
Brand: MedChemExpress
SKU: HY-132649S
Rating: 4.5 (1 reviews)

Cat. No.: HY-132649S Purity: 99%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

α-Cholestane-d₄ is the deuterium labeled α-Cholestane[1].

For research use only. We do not sell to patients.

α-Cholestane-d<sub>4</sub> Chemical Structure

α-Cholestane-d₄ Chemical Structure

CAS No. : 205529-74-4

Size	Price	Stock	Quantity
1 mg	USD 107	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 320	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 513	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

α-Cholestane-d₄ is the deuterium labeled α-Cholestane[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

376.69

Formula

C₂₇H₄₄D₄

CAS No.

205529-74-4

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](C([2H])([2H])CC([2H])([2H])C4)([H])CC3)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

Ethanol : 20 mg/mL (53.09 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6547 mL	13.2735 mL	26.5470 mL
5 mM	0.5309 mL	2.6547 mL	5.3094 mL
10 mM	0.2655 mL	1.3274 mL	2.6547 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (249 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	2.6547 mL	13.2735 mL	26.5470 mL	66.3676 mL
	5 mM	0.5309 mL	2.6547 mL	5.3094 mL	13.2735 mL
	10 mM	0.2655 mL	1.3274 mL	2.6547 mL	6.6368 mL
	15 mM	0.1770 mL	0.8849 mL	1.7698 mL	4.4245 mL
	20 mM	0.1327 mL	0.6637 mL	1.3274 mL	3.3184 mL
	25 mM	0.1062 mL	0.5309 mL	1.0619 mL	2.6547 mL
	30 mM	0.0885 mL	0.4425 mL	0.8849 mL	2.2123 mL
	40 mM	0.0664 mL	0.3318 mL	0.6637 mL	1.6592 mL
	50 mM	0.0531 mL	0.2655 mL	0.5309 mL	1.3274 mL