2. Neuronal Signaling
  3. Amyloid-β
  4. β-Amyloid peptide(16-20)

β-Amyloid peptide(16-20)  (Synonyms: KLVFF)

Cat. No.: HY-P5124 Purity: 99.70%
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β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility).

For research use only. We do not sell to patients.

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β-Amyloid peptide(16-20) Chemical Structure

β-Amyloid peptide(16-20) Chemical Structure

CAS No. : 153247-40-6

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5 mg USD 100 In-stock
10 mg USD 160 In-stock
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Based on 1 publication(s) in Google Scholar

β-Amyloid peptide(16-20) Related Antibodies

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Description

β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility)[1].

In Vitro

β-Amyloid peptide(16-20) (-NH2) inhibits Abeta fibril formation under a dose of 1:2 molar ratio (Aβ40/peptide), after incubation for 12 days (37 ℃)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

β-Amyloid peptide(16-20) Related Antibodies
Molecular Weight

652.82

Formula

C35H52N6O6
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Leu-Val-Phe-Phe
Sequence Shortening

KLVFF
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (51.06 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5318 mL 7.6591 mL 15.3182 mL
5 mM 0.3064 mL 1.5318 mL 3.0636 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.5318 mL 7.6591 mL 15.3182 mL 38.2954 mL
5 mM 0.3064 mL 1.5318 mL 3.0636 mL 7.6591 mL
10 mM 0.1532 mL 0.7659 mL 1.5318 mL 3.8295 mL
15 mM 0.1021 mL 0.5106 mL 1.0212 mL 2.5530 mL
20 mM 0.0766 mL 0.3830 mL 0.7659 mL 1.9148 mL
25 mM 0.0613 mL 0.3064 mL 0.6127 mL 1.5318 mL
30 mM 0.0511 mL 0.2553 mL 0.5106 mL 1.2765 mL
40 mM 0.0383 mL 0.1915 mL 0.3830 mL 0.9574 mL
50 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.7659 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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β-Amyloid peptide(16-20) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Amyloid peptide(16-20)153247-40-6 KLVFFAmyloid-ββ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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