2. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. GABA Receptor Endogenous Metabolite
  4. γ-Aminobutyric acid-d6

γ-Aminobutyric acid-d6  (Synonyms: 4-Aminobutyric acid-d6)

Cat. No.: HY-N0067S Purity: 99.90%
SDS COA Handling Instructions

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γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

For research use only. We do not sell to patients.

γ-Aminobutyric acid-d<sub>6</sub> Chemical Structure

γ-Aminobutyric acid-d6 Chemical Structure

CAS No. : 70607-85-1

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10 mg USD 350 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of γ-Aminobutyric acid-d6:

γ-Aminobutyric acid-d6 Related Antibodies

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Description

γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

γ-Aminobutyric acid-d6 Related Antibodies
Molecular Weight

109.16

Formula

C4H3D6NO2
CAS No.
Unlabeled CAS

56-12-2
Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (458.04 mM; Need ultrasonic)

H2O : 50 mg/mL (458.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.1609 mL 45.8043 mL 91.6086 mL
5 mM 1.8322 mL 9.1609 mL 18.3217 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.90%

SDS (394 KB)

COA (250 KB) HNMR (907 KB) RP-HPLC (363 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 9.1609 mL 45.8043 mL 91.6086 mL 229.0216 mL
5 mM 1.8322 mL 9.1609 mL 18.3217 mL 45.8043 mL
10 mM 0.9161 mL 4.5804 mL 9.1609 mL 22.9022 mL
15 mM 0.6107 mL 3.0536 mL 6.1072 mL 15.2681 mL
20 mM 0.4580 mL 2.2902 mL 4.5804 mL 11.4511 mL
25 mM 0.3664 mL 1.8322 mL 3.6643 mL 9.1609 mL
30 mM 0.3054 mL 1.5268 mL 3.0536 mL 7.6341 mL
40 mM 0.2290 mL 1.1451 mL 2.2902 mL 5.7255 mL
50 mM 0.1832 mL 0.9161 mL 1.8322 mL 4.5804 mL
60 mM 0.1527 mL 0.7634 mL 1.5268 mL 3.8170 mL
80 mM 0.1145 mL 0.5726 mL 1.1451 mL 2.8628 mL
100 mM 0.0916 mL 0.4580 mL 0.9161 mL 2.2902 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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γ-Aminobutyric acid-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

γ-Aminobutyric acid-d670607-85-14-Aminobutyric acid-d6GABA ReceptorEndogenous MetaboliteGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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