γ-Neuropeptide (rabbit) 

γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release^[1][2][3].

γ-Neuropeptide induces stimulation of LH release by hemipituitaries from intact male rats into the medium^[3].
γ-Neuropeptide (1 nM-100 nM) has no effect on GH release from male rats anterior pituitaries^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

γ-Neuropeptide 诱导完整雄性大鼠半垂体释放 LH 到培养基中^[3].
γ-Neuropeptide (1 nM-100 nM) 对雄性大鼠垂体前叶的 GH 释放没有影响^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2320.59

C₉₉H₁₅₈N₃₄O₂₉S

114882-65-4

Asp-Ala-Gly-His-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

DAGHGQISHKRHKTDSFVGLM-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Kage R, et al. Neuropeptide-gamma: a peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin. J Neurochem. 1988 May;50(5):1412-7.  [Content Brief]

  [2]. Yuan L, et al. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9.  [Content Brief]

  [3]. Debeljuk L, et al. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99.  [Content Brief]

  [4]. Kalra PS, et al. Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action. Endocrinology. 1992 Sep;131(3):1195-201.  [Content Brief]

  [5]. Debeljuk L, et al. In vivo and in vitro effects of neuropeptide K and neuropeptide gamma on the release of growth hormone. Neuroreport. 1995 Dec 15;6(18):2457-60.  [Content Brief]