2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. ω-Hydroxy-DEET

ω-Hydroxy-DEET is a major metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). ω-Hydroxy-DEET has anti-proliferative effects. DEET is a spatial repellent and an irritant that commonly used to prevent contact with mosquitoes.

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ω-Hydroxy-DEET Chemical Structure

ω-Hydroxy-DEET Chemical Structure

CAS No. : 72236-22-7

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Based on 1 publication(s) in Google Scholar

ω-Hydroxy-DEET Related Antibodies

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Description

ω-Hydroxy-DEET is a major metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). ω-Hydroxy-DEET has anti-proliferative effects. DEET is a spatial repellent and an irritant that commonly used to prevent contact with mosquitoes[1][2][3].

In Vitro

Hepatoma cell studies reveals that ω-Hydroxy-DEET (DHMB; 0.1-10 μg/mL; 48-72 hours) treatments decreases cellular proliferation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ω-Hydroxy-DEET Related Antibodies
In Vivo

The metabolite ω-Hydroxy-DEET (DHMB) is extensively distributed following intravenous and topical skin administration of DEET in rats. The ω-Hydroxy-DEET appeared to be the major metabolite for DEET. Repeated once-daily topical application for 30 days lead to higher concentrations of ω-Hydroxy-DEET in the liver[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

207.27

Formula

C12H17NO2
CAS No.
Appearance

Liquid (Density: 1.082±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(N(CC)CC)C1=CC=CC(CO)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation
References
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ω-Hydroxy-DEET Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ω-Hydroxy-DEET72236-22-7Drug MetaboliteDHMBmajormetaboliteDEETanti-proliferativespatialrepellentirritantInhibitorinhibitorinhibit

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