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  4. [1,1'-Biphenyl]-4-ylboronic acid

[1,1'-Biphenyl]-4-ylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

[1,1'-Biphenyl]-4-ylboronic acid Chemical Structure

[1,1'-Biphenyl]-4-ylboronic acid Chemical Structure

CAS No. : 5122-94-1

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Based on 1 publication(s) in Google Scholar

[1,1'-Biphenyl]-4-ylboronic acid Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

[1,1'-Biphenyl]-4-ylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cellular Effect
Cell Line Type Value Description References
HEK293 IC50
> 10 μM
Compound: 13
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated for 5 mins followed by capsiacin challenge by Fluo-4-AM dye based spectrofluorimetry
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated for 5 mins followed by capsiacin challenge by Fluo-4-AM dye based spectrofluorimetry
[PMID: 26850005]
In Vitro

4-Biphenylboronic acid is a boric acid compound.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[1,1'-Biphenyl]-4-ylboronic acid Related Antibodies
Molecular Weight

198.03

Formula

C12H11BO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OB(O)C1=CC=C(C2=CC=CC=C2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (504.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0497 mL 25.2487 mL 50.4974 mL
5 mM 1.0099 mL 5.0497 mL 10.0995 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.99%

SDS (393 KB)

COA (246 KB) HNMR (111 KB) RP-HPLC (225 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.0497 mL 25.2487 mL 50.4974 mL 126.2435 mL
5 mM 1.0099 mL 5.0497 mL 10.0995 mL 25.2487 mL
10 mM 0.5050 mL 2.5249 mL 5.0497 mL 12.6243 mL
15 mM 0.3366 mL 1.6832 mL 3.3665 mL 8.4162 mL
20 mM 0.2525 mL 1.2624 mL 2.5249 mL 6.3122 mL
25 mM 0.2020 mL 1.0099 mL 2.0199 mL 5.0497 mL
30 mM 0.1683 mL 0.8416 mL 1.6832 mL 4.2081 mL
40 mM 0.1262 mL 0.6312 mL 1.2624 mL 3.1561 mL
50 mM 0.1010 mL 0.5050 mL 1.0099 mL 2.5249 mL
60 mM 0.0842 mL 0.4208 mL 0.8416 mL 2.1041 mL
80 mM 0.0631 mL 0.3156 mL 0.6312 mL 1.5780 mL
100 mM 0.0505 mL 0.2525 mL 0.5050 mL 1.2624 mL
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[1,1'-Biphenyl]-4-ylboronic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[1,1'-Biphenyl]-4-ylboronic acid5122-94-1Biochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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