1,10-Bis(pyridinium)decane (Synonyms: Decamethylenebispyridinium dibromide)

Cat. No.: HY-W165085 Purity: 99.66%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1,10-Bis(pyridinium)decane is an acetylcholinesterase (AchE) inhibitor, with an IC₅₀ of 25.8 nM.

For research use only. We do not sell to patients.

1,10-Bis(pyridinium)decane Chemical Structure

CAS No. : 6266-40-6

Size	Price	Stock	Quantity
5 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 280	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 480	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 700	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 995	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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References
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Description

1,10-Bis(pyridinium)decane is an acetylcholinesterase (AchE) inhibitor, with an IC₅₀ of 25.8 nM^[1].

Molecular Weight

458.27

Formula

C₂₀H₃₀Br₂N₂

CAS No.

6266-40-6

Appearance

Solid

Color

White to off-white

SMILES

[N+]1(CCCCCCCCCC[N+]2=CC=CC=C2)=CC=CC=C1.[Br-].[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 175 mg/mL (381.87 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1821 mL	10.9106 mL	21.8212 mL
5 mM	0.4364 mL	2.1821 mL	4.3642 mL
10 mM	0.2182 mL	1.0911 mL	2.1821 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.66%

Select Batch:

Data Sheet (264 KB) SDS (393 KB)

COA (242 KB) HNMR (263 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Bunyapaiboonsri T, et al. Dynamic deconvolution of a pre-equilibrated dynamic combinatorial library of acetylcholinesterase inhibitors. Chembiochem. 2001 Jun 1;2(6):438-44. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.1821 mL	10.9106 mL	21.8212 mL	54.5530 mL
	5 mM	0.4364 mL	2.1821 mL	4.3642 mL	10.9106 mL
	10 mM	0.2182 mL	1.0911 mL	2.1821 mL	5.4553 mL
	15 mM	0.1455 mL	0.7274 mL	1.4547 mL	3.6369 mL
	20 mM	0.1091 mL	0.5455 mL	1.0911 mL	2.7276 mL
	25 mM	0.0873 mL	0.4364 mL	0.8728 mL	2.1821 mL
	30 mM	0.0727 mL	0.3637 mL	0.7274 mL	1.8184 mL
	40 mM	0.0546 mL	0.2728 mL	0.5455 mL	1.3638 mL
	50 mM	0.0436 mL	0.2182 mL	0.4364 mL	1.0911 mL
	60 mM	0.0364 mL	0.1818 mL	0.3637 mL	0.9092 mL
	80 mM	0.0273 mL	0.1364 mL	0.2728 mL	0.6819 mL
	100 mM	0.0218 mL	0.1091 mL	0.2182 mL	0.5455 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

1,10-Bis(pyridinium)decane Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,10-Bis(pyridinium)decane6266-40-6Decamethylenebispyridinium dibromideCholinesterase (ChE)HydrazidealdehydeneuroscienceInhibitorinhibitorinhibit

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