2. Metabolic Enzyme/Protease Apoptosis
  3. Phosphatase Apoptosis
  4. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine  (Synonyms: 16:1 PE)

Cat. No.: HY-157673
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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells.

For research use only. We do not sell to patients.

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine Chemical Structure

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine Chemical Structure

CAS No. : 61599-23-3

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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine Related Antibodies

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Description

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells[1].

In Vitro

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 1-100 μM; 24-48 hours) reduces NCI-H28 cell viability in a concentration-dependent manner (1-100 μM), but has no effect on Met5A (non-malignant mesothelial cells) cells[1].
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 100 μM; 10-60 minutes) tends to attenuate activity ofERK1/ERK2[1].
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 30-100 μM; 48 hours) significantly increases TUNEL-positive NCI-H28 cells, indicating apoptosis, with minimal effect on Met5A[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine Related Antibodies

Cell Viability Assay[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 1 μM, 10 μM, 100 μM
Incubation Time: 24 hours, 48 hours
Result: Reduced NCI-H28 cell viability in a concentration-dependent manner.

Western Blot Analysis[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 100 μM
Incubation Time: 10 minutes, 30 minutes, 60 minutes
Result: Attenuated phosphorylation of ERK1/2 in NCI-H28 cells.

Apoptosis Analysis[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 30 and 100 μM
Incubation Time: 48 hours
Result: Induced apoptosis in NCI-H28 cells.
Molecular Weight

687.93

Formula

C37H70NO8P
CAS No.
SMILES

CCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OCCN)(O)=O)COC(CCCCCCC/C=C\CCCCCC)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine61599-23-316:1 PEPhosphataseApoptosisInhibitorinhibitorinhibit

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