1,3-Diethyl 2-oxopropanedioate

Name: 1,3-Diethyl 2-oxopropanedioate
Brand: MedChemExpress
SKU: HY-W016802
Rating: 4.5 (1 reviews)

Cat. No.: HY-W016802 Purity: 99.00%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1,3-Diethyl 2-oxopropanedioate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

1,3-Diethyl 2-oxopropanedioate Chemical Structure

CAS No. : 609-09-6

Size	Price	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 27	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 27	In-stock	Estimated Time of Arrival: December 31
Liquid
10 g	USD 25	In-stock	Estimated Time of Arrival: December 31
25 g	USD 40	In-stock	Estimated Time of Arrival: December 31
50 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
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Description

1,3-Diethyl 2-oxopropanedioate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Molecular Weight

174.15

Formula

C₇H₁₀O₅

CAS No.

609-09-6

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(OCC)C(C(OCC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (574.22 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.7422 mL	28.7109 mL	57.4218 mL
5 mM	1.1484 mL	5.7422 mL	11.4844 mL
10 mM	0.5742 mL	2.8711 mL	5.7422 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (14.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (14.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.49%

Select Batch:

Data Sheet (241 KB) SDS (393 KB)

COA (245 KB) HNMR (91 KB) GC (208 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.7422 mL	28.7109 mL	57.4218 mL	143.5544 mL
	5 mM	1.1484 mL	5.7422 mL	11.4844 mL	28.7109 mL
	10 mM	0.5742 mL	2.8711 mL	5.7422 mL	14.3554 mL
	15 mM	0.3828 mL	1.9141 mL	3.8281 mL	9.5703 mL
	20 mM	0.2871 mL	1.4355 mL	2.8711 mL	7.1777 mL
	25 mM	0.2297 mL	1.1484 mL	2.2969 mL	5.7422 mL
	30 mM	0.1914 mL	0.9570 mL	1.9141 mL	4.7851 mL
	40 mM	0.1436 mL	0.7178 mL	1.4355 mL	3.5889 mL
	50 mM	0.1148 mL	0.5742 mL	1.1484 mL	2.8711 mL
	60 mM	0.0957 mL	0.4785 mL	0.9570 mL	2.3926 mL
	80 mM	0.0718 mL	0.3589 mL	0.7178 mL	1.7944 mL
	100 mM	0.0574 mL	0.2871 mL	0.5742 mL	1.4355 mL