2. Others Metabolic Enzyme/Protease
  3. Biochemical Assay Reagents Mitochondrial Metabolism
  4. 1-Hexanol

1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism.

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1-Hexanol Chemical Structure

1-Hexanol Chemical Structure

CAS No. : 111-27-3

Size Price Stock Quantity
Solution
10 mM * 1 mL in Ethanol In-stock
Liquid
500 mg In-stock
1 g   Get quote  
5 g   Get quote  

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Other Forms of 1-Hexanol:

1-Hexanol Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[1]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism[2].

In Vivo

5-Hydroxytryptophan (50-100 mg/kg, ip, single dose) increases the synthesis and release of 5-HT in the brain, thus activates 5-HT2 receptor and promotes the secretion of prolactin and ACTH in rats models[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats[1]
Dosage: 50-100 mg/kg
Administration: ip, single dose
Result: Increased the secretion of prolactin and ACTH.
Molecular Weight

102.18

Formula

C6H14O
CAS No.
Appearance

Liquid (Density: 0.820 g/cm3)

Color

Colorless to light yellow

SMILES

OCCCCCC
Structure Classification
Initial Source

Alfalfa Plant Bug
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

Ethanol : 100 mg/mL (978.69 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.7869 mL 48.9347 mL 97.8694 mL
5 mM 1.9574 mL 9.7869 mL 19.5739 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (24.47 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (24.47 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.35%

SDS (605 KB)

COA (240 KB) HNMR (116 KB) GC (216 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 9.7869 mL 48.9347 mL 97.8694 mL 244.6735 mL
5 mM 1.9574 mL 9.7869 mL 19.5739 mL 48.9347 mL
10 mM 0.9787 mL 4.8935 mL 9.7869 mL 24.4673 mL
15 mM 0.6525 mL 3.2623 mL 6.5246 mL 16.3116 mL
20 mM 0.4893 mL 2.4467 mL 4.8935 mL 12.2337 mL
25 mM 0.3915 mL 1.9574 mL 3.9148 mL 9.7869 mL
30 mM 0.3262 mL 1.6312 mL 3.2623 mL 8.1558 mL
40 mM 0.2447 mL 1.2234 mL 2.4467 mL 6.1168 mL
50 mM 0.1957 mL 0.9787 mL 1.9574 mL 4.8935 mL
60 mM 0.1631 mL 0.8156 mL 1.6312 mL 4.0779 mL
80 mM 0.1223 mL 0.6117 mL 1.2234 mL 3.0584 mL
100 mM 0.0979 mL 0.4893 mL 0.9787 mL 2.4467 mL
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1-Hexanol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Hexanol111-27-3Biochemical Assay ReagentsMitochondrial MetabolismInhibitorinhibitorinhibit

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