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  4. PEG300

PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol.

For research use only. We do not sell to patients.

PEG300 Chemical Structure

PEG300 Chemical Structure

CAS No. : 25322-68-3

Size Price Stock Quantity
Solvent
50 mL USD 50 In-stock
Solvent
100 mL USD 57 In-stock
200 mL   Get quote  
500 mL   Get quote  
Synthetic products have potential research and development risk.

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Customer Review

Based on 83 publication(s) in Google Scholar

Other Forms of PEG300:

PEG300 Related Antibodies

Top Publications Citing Use of Products

83 Publications Citing Use of MCE PEG300

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol[1][2].

In Vitro

The FDA has approved polyethylene glycol (PEG) for use as a vehicle or base in foods, cosmetics and pharmaceuticals, including injectable, topical, rectal and nasal formulations. PEG shows little toxicity, and is eliminated from the body intact by either the kidneys (for PEGs < 30 kDa) or in the faeces (for PEGs > 20 kDa). PEG lacks immunogenicity, and antibodies to PEG are generated in rabbits only if PEG is combined with highly immunogenic proteins[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PEG300 Related Antibodies
In Vivo

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
The final concentration of PEG300 can go up to 50% in the formulations for intravenous and intramuscular injection without any toxic effects. When administered orally, the highest concentration of PEG300 can reach up to 90%[4][5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

300.00

CAS No.
Appearance

Liquid (Density: 1.127 g/mL)

Color

Colorless to light yellow

SMILES

[H]OCCO[H].[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (333.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (166.67 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3333 mL 16.6667 mL 33.3333 mL
5 mM 0.6667 mL 3.3333 mL 6.6667 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥97.0%

COA (242 KB) HNMR (97 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.3333 mL 16.6667 mL 33.3333 mL 83.3333 mL
5 mM 0.6667 mL 3.3333 mL 6.6667 mL 16.6667 mL
10 mM 0.3333 mL 1.6667 mL 3.3333 mL 8.3333 mL
15 mM 0.2222 mL 1.1111 mL 2.2222 mL 5.5556 mL
20 mM 0.1667 mL 0.8333 mL 1.6667 mL 4.1667 mL
25 mM 0.1333 mL 0.6667 mL 1.3333 mL 3.3333 mL
30 mM 0.1111 mL 0.5556 mL 1.1111 mL 2.7778 mL
40 mM 0.0833 mL 0.4167 mL 0.8333 mL 2.0833 mL
50 mM 0.0667 mL 0.3333 mL 0.6667 mL 1.6667 mL
60 mM 0.0556 mL 0.2778 mL 0.5556 mL 1.3889 mL
80 mM 0.0417 mL 0.2083 mL 0.4167 mL 1.0417 mL
100 mM 0.0333 mL 0.1667 mL 0.3333 mL 0.8333 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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PEG300 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PEG30025322-68-3Polyethylene glycol 300PEG 300PEG-300Polyethylene glycol300Polyethylene glycol-300Biochemical Assay ReagentsimmunogenicbiocompatiblepolymergastrointestinalmarkerInhibitorinhibitorinhibit

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