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  3. 1-Methylpiperidin-4-ol

1-Methylpiperidin-4-ol  (Synonyms: N-Methyl-4-piperidinol)

Cat. No.: HY-W018626 Purity: 95.27%
Handling Instructions Technical Support

1-Methylpiperidin-4-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

1-Methylpiperidin-4-ol Chemical Structure

1-Methylpiperidin-4-ol Chemical Structure

CAS No. : 106-52-5

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

1-Methylpiperidin-4-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis sis of CaMKII, VEGFR and FGFR kinase Inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

115.17

Formula

C6H13NO

CAS No.
Appearance

<29°C Solid,>31°C Liquid

Color

Light yellow to yellow

SMILES

OC1CCN(C)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (1736.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.6828 mL 43.4141 mL 86.8282 mL
5 mM 1.7366 mL 8.6828 mL 17.3656 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.6828 mL 43.4141 mL 86.8282 mL 217.0704 mL
5 mM 1.7366 mL 8.6828 mL 17.3656 mL 43.4141 mL
10 mM 0.8683 mL 4.3414 mL 8.6828 mL 21.7070 mL
15 mM 0.5789 mL 2.8943 mL 5.7885 mL 14.4714 mL
20 mM 0.4341 mL 2.1707 mL 4.3414 mL 10.8535 mL
25 mM 0.3473 mL 1.7366 mL 3.4731 mL 8.6828 mL
30 mM 0.2894 mL 1.4471 mL 2.8943 mL 7.2357 mL
40 mM 0.2171 mL 1.0854 mL 2.1707 mL 5.4268 mL
50 mM 0.1737 mL 0.8683 mL 1.7366 mL 4.3414 mL
60 mM 0.1447 mL 0.7236 mL 1.4471 mL 3.6178 mL
80 mM 0.1085 mL 0.5427 mL 1.0854 mL 2.7134 mL
100 mM 0.0868 mL 0.4341 mL 0.8683 mL 2.1707 mL
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1-Methylpiperidin-4-ol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1-Methylpiperidin-4-ol
Cat. No.:
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