1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 10-Formyltetrahydrofolic acid disodium

10-Formyltetrahydrofolic acid disodium 

Cat. No.: HY-112169A Purity: ≥90.0%
COA Handling Instructions

10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines.

For research use only. We do not sell to patients.

10-Formyltetrahydrofolic acid disodium Chemical Structure

10-Formyltetrahydrofolic acid disodium Chemical Structure

CAS No. : 914800-65-0

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Other Forms of 10-Formyltetrahydrofolic acid disodium:

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Description

10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines[1].

In Vivo

10-Formyltetrahydrofolic acid disodium in the liver of male Sprague-Dawley rats increases significantly after 30 and 60 minutes by administration of 1.3 mmol/kg methionine[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

517.40

Formula

C20H21N7Na2O7

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(N(CC2NC3=C(NC(N)=NC3=O)NC2)C=O)C=C1)=O

Structure Classification
Initial Source
Shipping

Shipping with dry ice.

Storage

-80°C, protect from light, stored under nitrogen

Solvent & Solubility
In Vitro: 

DMSO : 1 mg/mL (1.93 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9327 mL 9.6637 mL 19.3274 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥90.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9327 mL 9.6637 mL 19.3274 mL 48.3185 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
10-Formyltetrahydrofolic acid disodium
Cat. No.:
HY-112169A
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