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  3. 15-Crown-5

15-Crown-5 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

15-Crown-5 Chemical Structure

15-Crown-5 Chemical Structure

CAS No. : 33100-27-5

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25 g In-stock
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Based on 1 publication(s) in Google Scholar

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Description

15-Crown-5 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of Carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride ide, for performing reduction reactions in hydrogen Solvents. Furthermore, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

220.26

Formula

C10H20O5

CAS No.
Appearance

Liquid (Density: 1.324 g/cm³)

Color

Colorless to light yellow

SMILES

C1COCCOCCOCCOCCO1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 200 mg/mL (908.02 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5401 mL 22.7004 mL 45.4009 mL
5 mM 0.9080 mL 4.5401 mL 9.0802 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.81%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5401 mL 22.7004 mL 45.4009 mL 113.5022 mL
5 mM 0.9080 mL 4.5401 mL 9.0802 mL 22.7004 mL
10 mM 0.4540 mL 2.2700 mL 4.5401 mL 11.3502 mL
15 mM 0.3027 mL 1.5134 mL 3.0267 mL 7.5668 mL
20 mM 0.2270 mL 1.1350 mL 2.2700 mL 5.6751 mL
25 mM 0.1816 mL 0.9080 mL 1.8160 mL 4.5401 mL
30 mM 0.1513 mL 0.7567 mL 1.5134 mL 3.7834 mL
40 mM 0.1135 mL 0.5675 mL 1.1350 mL 2.8376 mL
50 mM 0.0908 mL 0.4540 mL 0.9080 mL 2.2700 mL
60 mM 0.0757 mL 0.3783 mL 0.7567 mL 1.8917 mL
80 mM 0.0568 mL 0.2838 mL 0.5675 mL 1.4188 mL
100 mM 0.0454 mL 0.2270 mL 0.4540 mL 1.1350 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
15-Crown-5
Cat. No.:
HY-W007451
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