2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 17a-Hydroxypregnenolone-d3

17a-Hydroxypregnenolone-d3 is the deuterium labeled 17a-Hydroxypregnenolone. 17a-Hydroxypregnenolone is a pregnane steroid. 17a-Hydroxypregnenolone is a prohormone in the formation of dehydroepiandrosterone (DHEA).

For research use only. We do not sell to patients.

17a-Hydroxypregnenolone-d<sub>3</sub> Chemical Structure

17a-Hydroxypregnenolone-d3 Chemical Structure

CAS No. : 105078-92-0

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Based on 1 publication(s) in Google Scholar

Other Forms of 17a-Hydroxypregnenolone-d3:

17a-Hydroxypregnenolone-d3 Related Antibodies

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  • Purity & Documentation

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Description

17a-Hydroxypregnenolone-d3 is the deuterium labeled 17a-Hydroxypregnenolone. 17a-Hydroxypregnenolone is a pregnane steroid. 17a-Hydroxypregnenolone is a prohormone in the formation of dehydroepiandrosterone (DHEA).

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

17a-Hydroxypregnenolone-d3 Related Antibodies
Molecular Weight

335.50

Formula

C21H29D3O3
CAS No.
Unlabeled CAS

387-79-1
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2(O)C(C([2H])([2H])[2H])=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (24.83 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 8.33 mg/mL (24.83 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9806 mL 14.9031 mL 29.8063 mL
5 mM 0.5961 mL 2.9806 mL 5.9613 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

SDS (251 KB)

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.9806 mL 14.9031 mL 29.8063 mL 74.5156 mL
5 mM 0.5961 mL 2.9806 mL 5.9613 mL 14.9031 mL
10 mM 0.2981 mL 1.4903 mL 2.9806 mL 7.4516 mL
15 mM 0.1987 mL 0.9935 mL 1.9871 mL 4.9677 mL
20 mM 0.1490 mL 0.7452 mL 1.4903 mL 3.7258 mL
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17a-Hydroxypregnenolone-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

17a-Hydroxypregnenolone-d3105078-92-0Endogenous MetaboliteInhibitorinhibitorinhibit

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