2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. 17β-Estradiol sulfate-d4 sodium

17β-Estradiol sulfate-d4 sodium  (Synonyms: 17β-Estradiol 3-sulfate-d4 sodium)

Cat. No.: HY-141672S1 Purity: ≥99.0%
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17β-Estradiol sulfate-d4 (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2].

For research use only. We do not sell to patients.

17β-Estradiol sulfate-d<sub>4</sub> sodium Chemical Structure

17β-Estradiol sulfate-d4 sodium Chemical Structure

CAS No. : 352431-50-6

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1 mg USD 320 In-stock
5 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 17β-Estradiol sulfate-d4 sodium:

17β-Estradiol sulfate-d4 sodium Related Antibodies

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Description

17β-Estradiol sulfate-d4 (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

17β-Estradiol sulfate-d4 sodium Related Antibodies
Molecular Weight

378.45

Formula

C18H19D4NaO5S
CAS No.
Unlabeled CAS

4999-79-5
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC([2H])([2H])[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC([2H])=C(OS(=O)(O[Na])=O)C([2H])=C4CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

Ethanol : ≥ 10 mg/mL (26.42 mM)

DMF : ≥ 10 mg/mL (26.42 mM)

Ethanol : ≥ 10 mg/mL (26.42 mM)

DMSO : ≥ 10 mg/mL (26.42 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 10 mg/mL (26.42 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6424 mL 13.2118 mL 26.4236 mL
5 mM 0.5285 mL 2.6424 mL 5.2847 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMF / Ethanol / DMSO / DMF 1 mM 2.6424 mL 13.2118 mL 26.4236 mL 66.0589 mL
5 mM 0.5285 mL 2.6424 mL 5.2847 mL 13.2118 mL
10 mM 0.2642 mL 1.3212 mL 2.6424 mL 6.6059 mL
15 mM 0.1762 mL 0.8808 mL 1.7616 mL 4.4039 mL
20 mM 0.1321 mL 0.6606 mL 1.3212 mL 3.3029 mL
25 mM 0.1057 mL 0.5285 mL 1.0569 mL 2.6424 mL
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17β-Estradiol sulfate-d4 sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

17β-Estradiol sulfate-d4352431-50-617β-Estradiol 3-sulfate-d4GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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