1. Cell Cycle/DNA Damage Anti-infection
  2. Topoisomerase Bacterial
  3. (1R,2S,7R)-Sitafloxacin

(1R,2S,7R)-Sitafloxacin  (Synonyms: (1R,2S,7R)-DU-6859a; DU-6857)

Cat. No.: HY-B0395D
Handling Instructions Technical Support

(R)-Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase.

For research use only. We do not sell to patients.

(1R,2S,7R)-Sitafloxacin Chemical Structure

(1R,2S,7R)-Sitafloxacin Chemical Structure

CAS No. : 127254-10-8

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Description

(R)-Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase[1].

Molecular Weight

409.81

Formula

C19H18ClF2N3O3

CAS No.
SMILES

O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@@H]4N)CC54CC5)=C3Cl)C1=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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(1R,2S,7R)-Sitafloxacin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(1R,2S,7R)-Sitafloxacin
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HY-B0395D
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